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1

Probes for Narcotic Receptor Mediated Phenomena. Part 28: New Opioid Antagonists from Enantiomeric Analogues of 5-(3-Hydroxyphenyl)-N-phenylethylmorphan

Akihiro Hashimoto, Arthur E Jacobson, Richard B Rothman, Christina M Dersch, Clifford George, Judith L Flippen-Anderson, Kenner C Rice

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 290 KB

english, 2002

2

Factors Influencing Agonist Potency and Selectivity for the Opioid δ Receptor Are Revealed in Structure−Activity Relationship Studies of the 4-[(N-Substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides

Thomas, James B., Herault, Xavier M., Rothman, Richard B., Atkinson, Robert N., Burgess, Jason P., Mascarella, S. Wayne, Dersch, Christina M., Xu, Heng, Flippen-Anderson, Judith L., George, Clifford F

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 259 KB

english, 2001

3

Polyazapolycyclics by condensation of aldehydes with amines. 2. Formation of 2,4,6,8,10,12-hexabenzyl-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05.9.03,11]dodecanes from glyoxal and benzylamines

Nielsen, Arnold T., Nissan, Robin A., Vanderah, David J., Coon, Clifford L., Gilardi, Richard D., George, Clifford F., Flippen-Anderson, Judith

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 1.09 MB

english, 1990

4

Facile synthesis and nitration of cis-syn-cis-2,6-dioxodecahydro-1H,5H-diimidazo[4,5-b:4',5'-e]pyrazine

Vedachalam, Murugappa, Ramakrishnan, Vayalakkavoor T., Boyer, Joseph H., Dagley, Ian J., Nelson, Keith A., Adolph, Horst G., Gilardi, Richard, George, Clifford, Flippen-Anderson, Judith L.

Journal:

Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 962 KB

english, 1991

5

A New Class of Flexible Energetic Salts: The Crystal Structures of the Ammonium, Lithium, Potassium, and Cesium Salts of Dinitramide

Gilardi, Richard, Flippen-Anderson, J., George, Clifford, Butcher, Ray J.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 157 KB

english, 1997

6

Synthesis and Pharmacological Evaluation of 3-(3,4-Dichlorophenyl)-1-indanamine Derivatives as Nonselective Ligands for Biogenic Amine Transporters

Yu, Han, Kim, In Jong, Folk, John E., Tian, Xinrong, Rothman, Richard B., Baumann, Michael H., Dersch, Christina M., Flippen-Anderson, Judith L., Parrish, Damon, Jacobson, Arthur E., Rice, Kenner C.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 234 KB

english, 2004

7

Decamethylmanganocenium tetracyanoethenide, [Mn(C5Me5)2]⊙⊙⊕ [TCNE]⊙⊖—a molecular ferromagnet with an 8.8 K Tc

Dr. Joel S. Miller, Dr. David A. Dixon, R. Scott. McLean, David M. Groski, Dr. Richard B. Flippen, Dr. Juan M. Manriquez, Dr. Gordon T. Yee, K. S. Narayan, Prof. Arthur J. Epstein

Journal:

Advanced Materials

Year:

1991

Language:

english

File:

PDF, 269 KB

english, 1991

8

Novel Macrocyclic Trichothecenes from Myrothecium Roridum

Bruce B. Jarvis, F. Taha Çömezoglu, Yin-Won Lee, Judith L. Flippen-Anderson, Richard D. Gilardi, Clifford F. George

Journal:

Bulletin des Sociétés Chimiques Belges

Year:

1986

Language:

english

File:

PDF, 803 KB

english, 1986

9

ChemInform Abstract: Synthesis and Characterization of 5-Substituted 1,3-Diazacyclohexane Derivatives.

Theodore Axenrod, Jianguang Sun, Kajal K. Das, Paritosh R. Dave, Farhad Forohar, Mira Kaselj, Nirupam J. Trivedi, Richard D. Gilardi, Judith L. Flippen-Anderson

Journal:

Year:

2000

File:

PDF, 30 KB

2000

10

ChemInform Abstract: Design, Synthesis, and Monoamine Transporter Binding Site Affinities of Methoxy Derivatives of Indatraline.

Xiao-Hui Gu, Han Yu, Arthur E. Jacobson, Richard B. Rothman, Christina M. Dersch, Clifford George, Judith L. Flippen-Anderson, Kenner C. Rice

Journal:

Year:

2001

File:

PDF, 30 KB

2001

11

Structure-Activity Relationship of Oxygenated Morphinans. VII. 5-Methylated and 14-Hydroxy-substituted Agonists and Antagonists of the 4-Hydroxy- and 3, 4-Dioxygenated 6-Morphinanone Series

Arnold Brossi, Louise Atwell, Arthur E. Jacobson, Maria D. Rozwadowska, Helmut Schmidhammer, Judith L. Flippen-Anderson, Richard Gilardi

Journal:

Helvetica Chimica Acta

Year:

1982

Language:

english

File:

PDF, 716 KB

english, 1982

12

Apomorphinans from Isoquinolines: Grewe cyclization of 1-(2-hydroxybenzyl)-N-methyloctahydroisoquinoline and its O-methyl ether

Helmut Schmidhammer, Arnold Brossi, Judith L. Flippen-Anderson, Richard Gilardi

Journal:

Helvetica Chimica Acta

Year:

1983

Language:

english

File:

PDF, 320 KB

english, 1983

13

The chemistry of drugs part IV, Configurations of antimalarials derived from qinghaosu: Dihydroqingyhaosu, artemether, and artesunic acid

Xuan-De Luo, Herman J. C. Yeh, Arnold Brossi, Judith L. Flippen-Anderson, Richard Gillardi

Journal:

Helvetica Chimica Acta

Year:

1984

Language:

english

File:

PDF, 456 KB

english, 1984

14

Unusual behavior of 34:10,11-bis(2',3'-quinolino)tricyclo-[6.3.0.02,6] undecane upon attempted monoprotonation with triflic acid

Alan P. Marchand, Pendri Annapurna, Richard W. Taylor, Don L. Simmons, William H. Watson, Ante Nagl, Judith L. Flippen-Anderson, Richard Gilardi, Clifford George

Journal:

Year:

1990

Language:

english

File:

PDF, 426 KB

english, 1990

15

Synthesis of polyazapolycyclic caged polynitramines

Arnold T. Nielsen, Andrew P. Chafin, Stephen L. Christian, Donald W. Moore, Melvin P. Nadler, Robin A. Nissan, David J. Vanderah, Richard D. Gilardi, Clifford F. George, Judith L. Flippen-Anderson

Journal:

Year:

1998

Language:

english

File:

PDF, 1.68 MB

english, 1998

16

2,3:6,7-Bis(2′,3′-quinolino)pentacyclo[6.5.0.04,12.05,10.09,13]tridecane

Alan P Marchand, Pendri Annapurna, Judith L Flippen-Anderson, Richard Gilardi, Clifford George

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 198 KB

english, 1988

17

N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines are opioid receptor pure antagonists

James B. Thomas, S.Wayne Mascarella, Jason P. Burgess, Heng Xu, Karen B. McCullough, Richard B. Rothman, Judith L. Flippen-Anderson, Clifford F. George, Buddy E. Cantrell, Dennis M. Zimmerman, F.Ivy C

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 239 KB

english, 1998

18

Twins, disorders and other demons

Judith L Flippen-Anderson, Jeffrey R Deschamps, Richard D Gilardi, Clifford George

Journal:

Crystal Engineering

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

19

Distortions in nitramine substituted cubanes: The structures of N,N′-dinitro-1,4-diaminocubane, N,N′-dinitro-N,N′-(2-pyridyl)-1,4-diaminocubane, and 1,2,4,7-tetrakis(N-methoxycarbonylnitramino)cubane

Ray J. Butcher, Richard D. Gilardi, Clifford George, Judith Flippen-Anderson

Journal:

Journal of Chemical Crystallography

Year:

1996

Language:

english

File:

PDF, 531 KB

english, 1996

20

Diaryldimethylpiperazine ligands with μ- and δ-opioid receptor affinity: Synthesis of (+)-4-[(αR)-α-(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide and (−)-4-[(αR)-α-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide

In Jong Kim, Thomas Ullrich, James W. Janetka, M.Scott Furness, Arthur E. Jacobson, Richard B. Rothman, Christina M. Dersch, Judith L. Flippen-Anderson, Clifford George, Kenner C. Rice

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 261 KB

english, 2003

21

The Use of Nitrogen Dioxide to Improve the Superconducting Properties of YBa2Cu3O7

Kevin J. Leary, Howard W. Jacobson, Thomas R. Askew, Richard B. Flippen

Journal:

Journal of the American Ceramic Society

Year:

1990

Language:

english

File:

PDF, 650 KB

english, 1990

22

Substituted 1-(pyrrol-2-ylmethylene)pyrrolidinium salts a source of stable 2-azafulvenamines

Phillip E. Sonnet, Judith L. Flippen, Richard D. Gilardi

Journal:

Journal of Heterocyclic Chemistry

Year:

1974

File:

PDF, 146 KB

1974

23

Crystal structure of deltakephalin: a γ-selective opioid peptide with a novel β-bend-like conformation

JUDITH L. FLIPPEN-ANDERSON, JEFFREY R. DESCHAMPS, KEITH B. WARD, CLIFFORD GEORGE, RICHARD HOUGHTEN

Journal:

Chemical Biology & Drug Design

Year:

1994

Language:

english

File:

PDF, 554 KB

english, 1994

24

Particle Size Analysis

Barth, Howard G., Flippen, Richard B.

Journal:

Analytical Chemistry

Year:

1995

Language:

english

File:

PDF, 2.28 MB

english, 1995

25

Synthesis and reactions of 1,1-diiododinitroethylene

Baum, Kurt, Bigelow, Sean S., Nguyen Nghi Van,, Archibald, Thomas G., Gilardi, Richard, Flippen-Anderson, Judith L., George, Clifford

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 936 KB

english, 1992

26

Synthesis and Biological Evaluation of Tropane-like 1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine (GBR 12909) Analogues

Zhang, Ying, Joseph, David B., Bowen, Wayne D., Flippen-Anderson, Judith L., Dersch, Christina M., Rothman, Richard B., Jacobson, Arthur E., Rice, Kenner C.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 118 KB

english, 2001

27

Synthesis of 4,4,8,8,11,11-hexanitropentacyclo[5.4.0.02,6.03,10.05,9]undecane

Marchand, Alan P., Dave, Paritosh R., Rajapaksa, D., Arney, Benny E., Flippen-Anderson, Judith L., Gilardi, Richard, George, Clifford

Journal:

Journal of Organic Chemistry

Year:

1989

Language:

english

File:

PDF, 976 KB

english, 1989

28

Synthesis of nitro-substituted 2,3,4,8-tetraphenylpentacyclo[5.3.0.02,5.03,9.04,8]decanes

Marchand, Alan P., Annapurna, G. S., Vidyasagar, V., Flippen-Anderson, Judith L., Gilardi, Richard, George, Clifford, Ammon, Herman L.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 945 KB

english, 1987

29

Synthesis and Characterization of 5-Substituted 1,3-Diazacyclohexane Derivatives

Axenrod, Theodore, Sun, Jianguang, Das, Kajal K., Dave, Paritosh R., Forohar, Farhad, Kaselj, Mira, Trivedi, Nirupam J., Gilardi, Richard D., Flippen-Anderson, Judith L.

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 174 KB

english, 2000

30

1,3,4-THIADIAZOLES FROM THIOSEMICARBAZIDES

Scovill, John P., Klayman, Daniel L., Flippen-anderson, Judith L., Gilardi, Richard

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1991

Language:

english

File:

PDF, 409 KB

english, 1991

31

Synthesis and properties of 1,2-difluorodinitroethylene

Baum, Kurt, Archibald, Thomas G., Tzeng, Dongjaw, Gilardi, Richard, Flippen-Anderson, Judith L., George, Clifford

Journal:

Journal of Organic Chemistry

Year:

1991

Language:

english

File:

PDF, 401 KB

english, 1991

32

Lewis acid promoted reaction of pentacyclo[5.4.0.02,6.03,10.05,9]undecane-8,11-dione with ethyl diazoacetate: a synthetic entry into the pentacyclo[6.5.0.04,12.05,10.09,13]tridecane ring system

Marchand, Alan P., Arney, Benny E., Gilardi, Richard, Flippen-Anderson, Judith L.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 469 KB

english, 1987

33

Comparison of (-)-eseroline with (+)-eseroline and dihydroseco analogs in antinociceptive assays: confirmation of rubreserine structure by x-ray analysis

Schonenberger, Bernhard, Jacobson, Arthur E., Brossi, Arnold, Streaty, Richard, Klee, Werner A., Flippen-Anderson, Judith L., Gilardi, Richard

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 773 KB

english, 1986

34

Nitration of 1,1-diamino-2,2-dinitroethylenes

Baum, Kurt, Nguyen Nghi Van,, Gilardi, Richard, Flippen-Anderson, Judith L., George, Clifford

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 636 KB

english, 1992

35

(E)-8-Benzylidene Derivatives of 2-Methyl-5-(3-hydroxyphenyl)morphans: Highly Selective Ligands for the .sigma.2 Receptor Subtype

Bertha, Craig M., Vilner, Bertold J., Mattson, Mariena V., Bowen, Wayne D., Becketts, Karen, Xu, Heng, Rothman, Richard B., Flippen-Anderson, Judith L., Rice, Kenner C.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.51 MB

english, 1995

36

Probes for Narcotic Receptor Mediated Phenomena. 23. 1 Synthesis, Opioid Receptor Binding, and Bioassay of the Highly Selective δ Agonist (+)-4-[(α R )-α-((2 S ,5 R )-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N , N -diethylbenzamide (SNC 80) and Related Novel Nonpeptide δ Opioid Receptor Ligands

Calderon, Silvia N., Rice, Kenner C., Rothman, Richard B., Porreca, Frank, Flippen-Anderson, Judith L., Xu, Heng, Becketts, Karen, Smith, Larren E., Bilsky, Edward J., Davis, Peg, Horvath, Robert

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 356 KB

english, 1997

37

Probes for Narcotic Receptor-Mediated Phenomena. 20. Alteration of Opioid Receptor Subtype Selectivity of the 5-(3-Hydroxyphenyl)morphans by Application of the Message-Address Concept: Preparation of .delta.-Opioid Receptor Ligands

Bertha, Craig M., Flippen-Anderson, Judith L., Rothman, Richard B., Porreca, Frank, Davis, Peg, Xu, Heng, Becketts, Karen, Cha, Xian-Yuan, Rice, Kenner C.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.31 MB

english, 1995

38

The isolation of a bi(2,4,6,8-tetraazabicyclo[3.3.0]octane) from the reaction of glyoxal with benzylamine

Chaykovsky, Michael, Koppes, William M., Russell, Thomas P., Gilardi, Richard, George, Clifford, Flippen-Anderson, Judith L.

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 419 KB

english, 1992

39

Considered synthetic methods and reactions. Part 165. One-step preparation of hydrazinium nitrates from tertiary amines and azaarenes with hydroxylamine-O-sulfonic acid/barium nitrate/barium oxide and conversion to energetic amine-nitroimides

Olah, George A., Sassaman, Mark B., Zuanic, Miljenko, Rao, Chandra B., Prakash, G. K. Surya, Gilardi, Richard, Flippen-Anderson, Judith, George, Clifford

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 519 KB

english, 1992

40

A Marked Change of Receptor Affinity of the 2-Methyl-5-(3-hydroxyphenyl)morphans upon Attachment of an (E)-8-Benzylidene Moiety: Synthesis and Evaluation of a New Class of .sigma. Receptor Ligands

Bertha, Craig M., Mattson, Mariena V., Flippen-Anderson, Judith L., Rothman, Richard B., Xu, Heng, Cha, Xian-Yuan, Becketts, Karen, Rice, Kenner C.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.23 MB

english, 1994

41

N-Substituted 9β-Methyl-5-(3-hydroxyphenyl)morphans Are Opioid Receptor Pure Antagonists

Thomas, James B., Zheng, Xiaoling, Mascarella, S. Wayne, Rothman, Richard B., Dersch, Christina M., Partilla, John S., Flippen-Anderson, Judith L., George, Clifford F., Cantrell, Buddy E., Zimmerman,

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 190 KB

english, 1998

42

Crystal structures, molecular conformations, infrared spectra, and carbon-13 NMR spectra of methylproline peptides in the solid state

Flippen-Anderson, Judith L., Gilardi, Richard, Karle, Isabella L., Frey, Michael H., Opella, Stanley J., Gierasch, Lila M., Goodman, Murray, Madison, Vincent, Delaney, Norma G.

Journal:

Journal of the American Chemical Society

Year:

1983

Language:

english

File:

PDF, 712 KB

english, 1983

43

Regiospecific oxidation of binor S and acid-catalyzed rearrangement of the product to the first example of a pentacyclo[6.6.0.05,14.07,12.09,13]tetradecane

Pramod, Kakumanu, Eaton, Philip E., Gilardi, Richard, Flippen-Anderson, Judith L.

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 417 KB

english, 1990

44

Conformation of the tetrasaccharide stachyose

Gilardi, Richard D., Flippen, Judith L.

Journal:

Journal of the American Chemical Society

Year:

1975

Language:

english

File:

PDF, 361 KB

english, 1975

45

Design, Synthesis, and Monoamine Transporter Binding Site Affinities of Methoxy Derivatives of Indatraline

Gu, Xiao-Hui, Yu, Han, Jacobson, Arthur E., Rothman, Richard B., Dersch, Christina M., George, Clifford, Flippen-Anderson, Judith L., Rice, Kenner C.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

46

Conformational effects in trichothecenes: structures of 15-hydroxy C4 and C8 ketones

Jarvis, Bruce B., Mazzocchi, Dorothy Bruns, Ammon, Herman L., Mazzola, Eugene P., Flippen-Anderson, Judith L., Gilardi, Richard D., George, Clifford F.

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 424 KB

english, 1990

47

Probes for Narcotic Receptor Mediated Phenomena. 19. Synthesis of (+)-4-[(.alpha.R)-.alpha.-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC 80): A Highly Selective, Nonpeptide .delta. Opioid Receptor Agonist

Calderon, Silvia N., Rothman, Richard B., Porreca, Frank, Flippen-Anderson, Judith L., McNutt, Robert W., Xu, Heng, Smith, Larren E., Bilsky, Edward J., Davis, Peg, Rice, Kenner C.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 490 KB

english, 1994

48

Free-radical arylation of cubane using cubyl lead acylates

Moriarty, Robert M., Khosrowshahi, Jaffar S., Miller, Richard S., Flippen-Andersen, Judith, Gilardi, Richard

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 270 KB

english, 1989

49

Probes for Narcotic Receptor-Mediated Phenomena. 25. 1 Synthesis and Evaluation of N -Alkyl-Substituted (α-Piperazinylbenzyl)benzamides as Novel, Highly Selective δ Opioid Receptor Agonists

Katsura, Yousuke, Zhang, Xiaoyan, Homma, Koichi, Rice, Kenner C., Calderon, Silvia N., Rothman, Richard B., Yamamura, Henry I., Davis, Peg, Flippen-Anderson, Judith L., Xu, Heng, Becketts, Karen, Folt

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 387 KB

english, 1997

50

Isolation and identification of novel lactones from male Mexican fruit flies

Stokes, Jerry B., Uebel, Edward C., Warthen, John D., Jacobson, Martin, Flippen-Anderson, Judith L., Gilardi, Richard, Spishakoff, Leonard M., Wilzer, Kenneth R.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1983

Language:

english

File:

PDF, 766 KB

english, 1983